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Trifluoromethanesulfonic acid CAS#1493-13-6

  • Trifluoromethanesulfonic acid CAS#1493-13-6
  • Trifluoromethanesulfonic acid CAS#1493-13-6
  • Trifluoromethanesulfonic acid CAS#1493-13-6
  • Trifluoromethanesulfonic acid CAS#1493-13-6
  • Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid CAS#1493-13-6

Extremely Strong Acid：Triflic acid is recognized as one of the strongest acids, belonging to the superacid class.


High Thermal and Chemical Stability：It is non-oxidizing, thermally stable, and resistant to both oxidation and reduction.


Versatile in Fine Chemical and Pharmaceutical Synthesis：Used in the production of pharmaceuticals, agricultural chemicals, polymers, nucleosides, antibiotics, steroids, proteins, and glycosides.


Effective Anhydrous Form: The anhydrous form is widely utilized in fine chemical synthesis due to its reactivity and utility.

Phone ：+86 18626059817
WhatsApp ：+86 18626059817
Email ：cora@wxqysteel.com
product description

Product Description of Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid (triflic acid, TfOH) has the formula CF3SO3H and is classified as a superacid, ranking among the strongest acids known.

It features non-oxidizing property, high thermal stability, and resistance to oxidation and reduction. Widely applied in pharmaceuticals, agrochemicals and polymer synthesis, its anhydrous form is especially valuable for fine chemical production.

In pharma manufacturing, it is used to synthesize nucleosides, antibiotics, steroids, proteins and glycosides. Triflic anhydride is highly reactive with water and has significant toxicity.


Product Application of Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid acts as a catalyst for Friedel-Crafts acylation, alkylation and polymerization reactions. It also serves as a solvent for ESR analysis and a strong non-aqueous acid titrant. Combined with trifluoroacetic acid, it is used in solid-phase peptide synthesis. It is acknowledged as one of the strongest monoprotic acids.

Product Information

Parameters


Melting point-40 °C
Boiling point162 °C (lit.)
density1.696 g/mL at 25 °C (lit.)
vapor density5.2 (vs air)
vapor pressure8 mm Hg ( 25 °C)
refractive indexn20/D 1.327(lit.)
RTECSPB2771000
FpNone
storage temp.Store below +30°C.
solubilityMiscible in H2O
pka-14(at 25℃)
formFuming Liquid
colorslightly brown
Specific Gravity1.696
PH<1 (H2O)
Water SolubilitySOLUBLE
SensitiveHygroscopic
Merck149,676
BRN1812100
Stability:Stable. Incompatible with acids, alkalis, metals.
InChIKeyITMCEJHCFYSIIV-UHFFFAOYSA-N
LogP0.3 at 25℃
CAS DataBase Reference1493-13-6(CAS DataBase Reference)
NIST Chemistry ReferenceCF3SO3H(1493-13-6)
EPA Substance Registry SystemMethanesulfonic acid, trifluoro- (1493-13-6)
Hazard CodesC
Risk Statements21/22-35-10
Safety Statements26-36/37/39-45
RIDADRUN 3265 8/PG 2
WGK Germany2
F3-10
Hazard NoteCorrosive/Hygroscopic
TSCAYes
HazardClass8
PackingGroupII
HS Code29049020
ToxicityLD50 orally in Rabbit: 1605 mg/kg LD50 dermal Rat > 2000 mg/kg


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Usage Guidance: Assistance with adjusting processing parameters (if required).
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