Bronopol CAS#52-51-7

Bronopol CAS#52-51-7

Effective Antimicrobial Agent:Bronopol acts as a preservative and biocide, preventing microbial growth in various formulations.


Versatile Usage:It can be incorporated into multiple products, including lubricants and cosmetic or pharmaceutical preparations.


Water-Soluble:Its solubility in water allows easy formulation and dispersion in aqueous products.


Stability in Formulations:Bronopol maintains antimicrobial efficacy over time, supporting long shelf-life of the products it protects.


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product description

Product Application of Bronopol CAS#52-51-7

Bronopol is a formaldehyde-releasing compound and has been identified as a potential allergen for dairy workers. In a reported case, bronopol contained in ultrasound lubricant jelly induced contact dermatitis in a veterinary surgeon.


Product Application of Bronopol CAS#52-51-7

Bronopol is used as an antimicrobial preservative at a concentration of 0.01–0.1% w/v, either alone or blended with other preservatives. It is applied in topical pharmaceuticals, cosmetics and personal care products, with a typical dosage of 0.02% w/v.

Product Information

Parameters


Melting point130-133 °C(lit.)
Boiling point358.0±42.0 °C(Predicted)
density2.0002 (rough estimate)
refractive index1.6200 (estimate)
Fp167°C
storage temp.Inert atmosphere,Room Temperature
solubilityH2O: soluble100mg/mL, clear, colorless to faintly yellow
pka12.02±0.10(Predicted)
formCrystals or Crystalline Powder
colorWhite to yellow
Odorodorless
Water Solubility25 g/100 mL (22 ºC)
Merck141447
BRN1705868
Stability:Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.
Major Applicationagriculture
cleaning products
cosmetics
environmental
food and beverages
personal care
Cosmetics Ingredients FunctionsPRESERVATIVE
Cosmetic Ingredient Review (CIR)Bronopol (52-51-7)
InChI1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2
InChIKeyLVDKZNITIUWNER-UHFFFAOYSA-N
SMILESOCC(Br)(CO)[N+]([O-])=O
LogP1.150 (est)
CAS DataBase Reference52-51-7(CAS DataBase Reference)
NIST Chemistry ReferenceBronopol(52-51-7)
EPA Substance Registry SystemBronopol (52-51-7)


Safety Information


Hazard CodesXn,N
Risk Statements21/22-37/38-41-50
Safety Statements26-37/39-61-36/37/39
RIDADRUN 3241 4.1/PG 3
WGK Germany2
RTECSTY3385000
F4.2-8-9-21
TSCATSCA listed
HazardClass4.1
PackingGroupIII
HS Code29055999
Storage Class4.1B - Flammable solid hazardous materials
Hazard ClassificationsAcute Tox. 4 Dermal
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data52-51-7(Hazardous Substances Data)
ToxicityLD50 in mice, rats (mg/kg): 350, 400 orally (Croshaw)


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FAQ
Q:

Are you a manufacturer or a trader?

A:
We are a supply chain service provider rather than a single manufacturer. Instead of being tied to one specific factory, we have established deep partnerships with numerous high-quality domestic chemical enterprises that hold certifications such as ISO and REACH. This allows us to flexibly match the most suitable supply sources to your needs while independently conducting third-party quality inspections to ensure delivery quality and price competitiveness.
Q:

How do your overseas warehouses operate, and what are the practical benefits?

A:
We maintain transit warehouses with standing inventory in Southeast Asia, the Middle East, and Eastern Europe.
For you: You can pick up goods directly from local warehouses without the need for full-container orders; delivery times are reduced from the standard 30–45 days to just 3–5 days.
Reduced inventory pressure: You can purchase small batches for trial and quality verification before scaling up orders, avoiding the need to tie up large amounts of capital upfront.
Emergency restocking: If your production line faces a sudden material shortage, we can urgently dispatch supplies from our regional warehouses to prevent production downtime.
Q:

What is the Minimum Order Quantity (MOQ)?

A:
For standard products, the MOQ is typically one 20-foot container (approx. 16–20 tons) for direct shipments from China. However, for stock picked up from overseas warehouses, we support orders starting from 1 ton—ideal for sample testing or small-batch production. Specific MOQs depend on the product category and packaging type; please contact us for details.
Q:

How do you ensure product quality?

A:
We implement a "three-level quality control" system:
Before leaving the factory: We require the factory to provide a Certificate of Analysis (COA) for the specific batch.
Before shipment: We commission international third-party agencies like SGS or Intertek to conduct random inspections, with costs covered by us (for long-term partners).
After arrival: If quality issues arise, we commit to unconditional negotiation regarding returns, exchanges, or compensation, and we assume full responsibility. All terms are stipulated in the contract.
Q:

What payment methods do you accept? Do you offer credit terms?

A:
We accept T/T (Telegraphic Transfer), L/C (Letter of Credit at sight or usance), and D/P (Documents against Payment). For clients with a long-standing partnership and good credit standing, we offer partial credit terms (e.g., 30–60 days), subject to negotiation based on transaction history and due diligence results. Cash on Delivery (COD) is available for local customers ordering in-stock items from our overseas warehouses.
Q:

What is the typical delivery lead time?

A:
FOB (China Port): Goods are prepared and shipped within 7–15 working days after the contract is signed and the prepayment is received.
Overseas Warehouse Stock: Items are dispatched within 1–3 working days of order confirmation and payment; local delivery typically takes 2–5 days (depending on the country).
Q:

Which trade terms do you offer? Do you support DDP (Delivered Duty Paid)?

A:
We are proficient in handling common terms such as FOB, CIF, CFR, and EXW. Additionally, for regions covered by our overseas warehouses, we offer DDP services (including duties and door-to-door delivery), allowing you to receive goods without the hassle of complex import customs clearance procedures. Please consult your sales manager for specific costs.
Q:

How can I obtain samples? What are the costs?

A:
If stock is available at an overseas warehouse, we can provide 1–2 kg of samples for free; you only need to cover the local courier fees.
If shipping from China, we can arrange delivery via DHL or FedEx; samples are free, but you bear the international shipping costs. Once a clear intent to cooperate is established, these shipping costs can be deducted from your first order.
Q:

Can the contract price be adjusted if product prices fluctuate?

A:
We offer a price protection mechanism:
For fixed-price contracts, we do not unilaterally raise prices due to market increases.
If you anticipate a market downturn, we can negotiate floating pricing—settling based on a benchmark price on the date of shipment or arrival—to flexibly manage fluctuations.
Q:

What does your after-sales service include?

A:
We provide full-lifecycle service:
Usage Guidance: Assistance with adjusting processing parameters (if required).
Complaint Handling: Response within 48 hours and a solution provided within 7 days.
Regular follow-ups: Proactive contact every six months to understand changing needs and optimize supply solutions.
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