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Progesterone CAS#57-83-0

  • Progesterone CAS#57-83-0
  • Progesterone CAS#57-83-0
  • Progesterone CAS#57-83-0
  • Progesterone CAS#57-83-0
  • Progesterone CAS#57-83-0

Progesterone CAS#57-83-0

Natural Endogenous Progestogen Hormone：Progesterone is the body’s primary naturally occurring progestogen, secreted by the ovarian luteal cells, ensuring excellent biological relevance and compatibility.


Key Steroid Hormone Intermediate：It serves as an important intermediate for the synthesis of all steroid hormones, making it highly valuable in pharmaceutical and hormone-related applications.


Dual Crystal Forms with Identical Activity：Available in both α-type and β-type crystal forms, both providing the same physiological activity for flexible formulation use.


Excellent Solvent Compatibility：Although insoluble in water, progesterone is readily soluble in ethanol, ether, chloroform, acetone, dioxane, and concentrated sulfuric acid, supporting diverse processing and formulation requirements.



Phone ：+86 18626059817
WhatsApp ：+86 18626059817
Email ：cora@wxqysteel.com
product description

Products Description of Progesterone CAS#57-83-0

Progesterone is an endogenous steroid hormone mainly secreted by ovaries, acting as a major natural progestogen and key intermediate for steroid hormone synthesis.

It has two crystal forms with identical bioactivity. Insoluble in water, it dissolves readily in most organic solvents and concentrated sulfuric acid.


Product Application of Progesterone CAS#57-83-0

Progesterone cooperates with estrogen to transform endometrium for embryo implantation, maintains pregnancy by restraining uterine contraction, and facilitates breast development for lactation. High doses suppress ovulation via hormonal feedback.

It is clinically applied to treat threatened abortion, irregular bleeding, dysmenorrhea, amenorrhea and other gynecological disorders, as well as prostatic hyperplasia and related complications.


Product Information

Parameters


Melting point128-132 °C (lit.)
alpha186 º (c=1, ethanol)
Boiling point394.13°C (rough estimate)
densityd23 1.166; d20 1.171
refractive index182 ° (C=2, Dioxane)
Fp2℃
storage temp.room temp
solubilityH2O: 25 mg/mL, may be clear to slightly hazy
formpowder
colorYellow to yellow-brown
biological sourcesynthetic (organic)
Water Solubility<0.1 g/100 mL at 19 ºC
Merck7773
BRN1915950
BCS Class4
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyRJKFOVLPORLFTN-LEKSSAKUSA-N
LogP3.87
CAS DataBase Reference57-83-0(CAS DataBase Reference)
NIST Chemistry ReferenceProgesterone(57-83-0)
EPA Substance Registry SystemProgesterone (57-83-0)


Safety Information


Hazard CodesXn,T,F
Risk Statements40-45-62-36-20/21/22-11
Safety Statements36/37-45-53-16
RIDADRUN 1648 3 / PGII
WGK Germany3
RTECSTW0175000
HS Code29372390
Hazardous Substances Data57-83-0(Hazardous Substances Data)
ToxicityLD50 intraperitoneal in rat: 327mg/kg









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We are a supply chain service provider rather than a single manufacturer. Instead of being tied to one specific factory, we have established deep partnerships with numerous high-quality domestic chemical enterprises that hold certifications such as ISO and REACH. This allows us to flexibly match the most suitable supply sources to your needs while independently conducting third-party quality inspections to ensure delivery quality and price competitiveness.
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How do your overseas warehouses operate, and what are the practical benefits?

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We maintain transit warehouses with standing inventory in Southeast Asia, the Middle East, and Eastern Europe.
For you: You can pick up goods directly from local warehouses without the need for full-container orders; delivery times are reduced from the standard 30–45 days to just 3–5 days.
Reduced inventory pressure: You can purchase small batches for trial and quality verification before scaling up orders, avoiding the need to tie up large amounts of capital upfront.
Emergency restocking: If your production line faces a sudden material shortage, we can urgently dispatch supplies from our regional warehouses to prevent production downtime.
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What is the Minimum Order Quantity (MOQ)?

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For standard products, the MOQ is typically one 20-foot container (approx. 16–20 tons) for direct shipments from China. However, for stock picked up from overseas warehouses, we support orders starting from 1 ton—ideal for sample testing or small-batch production. Specific MOQs depend on the product category and packaging type; please contact us for details.
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How do you ensure product quality?

A：
We implement a "three-level quality control" system:
Before leaving the factory: We require the factory to provide a Certificate of Analysis (COA) for the specific batch.
Before shipment: We commission international third-party agencies like SGS or Intertek to conduct random inspections, with costs covered by us (for long-term partners).
After arrival: If quality issues arise, we commit to unconditional negotiation regarding returns, exchanges, or compensation, and we assume full responsibility. All terms are stipulated in the contract.
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We accept T/T (Telegraphic Transfer), L/C (Letter of Credit at sight or usance), and D/P (Documents against Payment). For clients with a long-standing partnership and good credit standing, we offer partial credit terms (e.g., 30–60 days), subject to negotiation based on transaction history and due diligence results. Cash on Delivery (COD) is available for local customers ordering in-stock items from our overseas warehouses.
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What is the typical delivery lead time?

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FOB (China Port): Goods are prepared and shipped within 7–15 working days after the contract is signed and the prepayment is received.
Overseas Warehouse Stock: Items are dispatched within 1–3 working days of order confirmation and payment; local delivery typically takes 2–5 days (depending on the country).
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Which trade terms do you offer? Do you support DDP (Delivered Duty Paid)?

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We are proficient in handling common terms such as FOB, CIF, CFR, and EXW. Additionally, for regions covered by our overseas warehouses, we offer DDP services (including duties and door-to-door delivery), allowing you to receive goods without the hassle of complex import customs clearance procedures. Please consult your sales manager for specific costs.
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How can I obtain samples? What are the costs?

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If stock is available at an overseas warehouse, we can provide 1–2 kg of samples for free; you only need to cover the local courier fees.
If shipping from China, we can arrange delivery via DHL or FedEx; samples are free, but you bear the international shipping costs. Once a clear intent to cooperate is established, these shipping costs can be deducted from your first order.
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Can the contract price be adjusted if product prices fluctuate?

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We offer a price protection mechanism:
For fixed-price contracts, we do not unilaterally raise prices due to market increases.
If you anticipate a market downturn, we can negotiate floating pricing—settling based on a benchmark price on the date of shipment or arrival—to flexibly manage fluctuations.
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What does your after-sales service include?

A：
We provide full-lifecycle service:
Usage Guidance: Assistance with adjusting processing parameters (if required).
Complaint Handling: Response within 48 hours and a solution provided within 7 days.
Regular follow-ups: Proactive contact every six months to understand changing needs and optimize supply solutions.
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