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Isoniazid CAS#54-85-3

  • Isoniazid CAS#54-85-3
  • Isoniazid CAS#54-85-3
  • Isoniazid CAS#54-85-3
  • Isoniazid CAS#54-85-3
  • Isoniazid CAS#54-85-3

Isoniazid CAS#54-85-3

Excellent Stability and Water Solubility: Isoniazid is chemically stable and readily soluble in water, supporting convenient formulation and broad application use.


Strong Reducing Properties: The hydrazine group provides excellent reducing capability, enabling reactions such as the conversion of dissolved oxygen to hydrogen peroxide under alkaline conditions.


Versatile Chemical Reactivity: Its active amino group (-NH₂) allows efficient reactions with carbonyl compounds, carboxylic acid derivatives, and sulfonyl chlorides, making it a valuable intermediate for derivative synthesis.


Suitable for Analytical and Luminescent Systems: It can participate in gold nanoparticle-catalyzed luminol luminescent systems, offering potential advantages in analytical and detection applications.


Phone ：+86 18626059817
WhatsApp ：+86 18626059817
Email ：cora@wxqysteel.com
product description

Product Description of Isoniazid CAS#54-85-3

Isoniazid is colorless or white crystalline powder with slight bitterness, stable and easily soluble in water.

Its hydrazine group has strong reducibility, capable of reducing dissolved oxygen under alkaline conditions for luminescent analysis use. Its amino group enables reactions to synthesize Schiff bases and various isoniazid derivatives.


Product Application of Isoniazid CAS#54-85-3

Isoniazid is a first-line, affordable anti-tuberculosis drug with high efficacy and low toxicity, also used as electroplating additive and chemical intermediate.
It can undergo condensation reactions to form multiple derivatives with anti-tuberculosis effects. Isoniazid shows the strongest potency, while its hydrazone has weaker antibacterial action yet lower neuro and hepatic toxicity.
It features strong selective inhibition against tubercle bacilli, achieving bacteriostasis at low concentrations and sterilization at higher doses for clinical and research use.
Product Information

Parameters


Melting point171-173 °C (lit.)
Boiling point251.97°C (rough estimate)
density1.2620 (rough estimate)
bulk density800kg/m3
refractive index1.6910 (estimate)
Fp>250°C
storage temp.2-8°C
solubility125g/l
formCrystals or Crystalline Powder
pkapKa 2.00/3.60/10.8(H2O) (Uncertain)
colorWhite or colorless
PH6-8 (50g/l, H2O, 20℃)
OdorOdorless
PH Range5.5 - 6.5 at 10 g/l at 25 °C
Water Solubility14 g/100 mL (25 ºC)
SensitiveAir Sensitive
Merck145186
BRN119374
BCS Class1,3
Stability:Stability Stable, but may be air or light sensitive. Combustible. Incompatible with strong oxidizing agents, chloral, aldehydes, iodine, ferric salts, hypochlorites.
InChIKeyQRXWMOHMRWLFEY-UHFFFAOYSA-N
CAS DataBase Reference54-85-3(CAS DataBase Reference)
NIST Chemistry ReferenceIsoniazid(54-85-3)
IARC3 (Vol. 4, Sup 7) 1987
EPA Substance Registry SystemIsoniazid (54-85-3)


Safety Information


Hazard CodesXn
Risk Statements22-38-40-36/37/38
Safety Statements37-36/37/39-26
RIDADR2811
WGK Germany3
RTECSNS1751850
TSCAYes
PackingGroupIII
HS Code29333999
Hazardous Substances Data54-85-3(Hazardous Substances Data)
ToxicityLD50 in mice (mg/kg): 151 i.p., 149 i.v. (Jenney, Pfeiffer)


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We are a supply chain service provider rather than a single manufacturer. Instead of being tied to one specific factory, we have established deep partnerships with numerous high-quality domestic chemical enterprises that hold certifications such as ISO and REACH. This allows us to flexibly match the most suitable supply sources to your needs while independently conducting third-party quality inspections to ensure delivery quality and price competitiveness.
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How do your overseas warehouses operate, and what are the practical benefits?

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We maintain transit warehouses with standing inventory in Southeast Asia, the Middle East, and Eastern Europe.
For you: You can pick up goods directly from local warehouses without the need for full-container orders; delivery times are reduced from the standard 30–45 days to just 3–5 days.
Reduced inventory pressure: You can purchase small batches for trial and quality verification before scaling up orders, avoiding the need to tie up large amounts of capital upfront.
Emergency restocking: If your production line faces a sudden material shortage, we can urgently dispatch supplies from our regional warehouses to prevent production downtime.
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What is the Minimum Order Quantity (MOQ)?

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For standard products, the MOQ is typically one 20-foot container (approx. 16–20 tons) for direct shipments from China. However, for stock picked up from overseas warehouses, we support orders starting from 1 ton—ideal for sample testing or small-batch production. Specific MOQs depend on the product category and packaging type; please contact us for details.
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How do you ensure product quality?

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We implement a "three-level quality control" system:
Before leaving the factory: We require the factory to provide a Certificate of Analysis (COA) for the specific batch.
Before shipment: We commission international third-party agencies like SGS or Intertek to conduct random inspections, with costs covered by us (for long-term partners).
After arrival: If quality issues arise, we commit to unconditional negotiation regarding returns, exchanges, or compensation, and we assume full responsibility. All terms are stipulated in the contract.
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We accept T/T (Telegraphic Transfer), L/C (Letter of Credit at sight or usance), and D/P (Documents against Payment). For clients with a long-standing partnership and good credit standing, we offer partial credit terms (e.g., 30–60 days), subject to negotiation based on transaction history and due diligence results. Cash on Delivery (COD) is available for local customers ordering in-stock items from our overseas warehouses.
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What is the typical delivery lead time?

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FOB (China Port): Goods are prepared and shipped within 7–15 working days after the contract is signed and the prepayment is received.
Overseas Warehouse Stock: Items are dispatched within 1–3 working days of order confirmation and payment; local delivery typically takes 2–5 days (depending on the country).
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Which trade terms do you offer? Do you support DDP (Delivered Duty Paid)?

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We are proficient in handling common terms such as FOB, CIF, CFR, and EXW. Additionally, for regions covered by our overseas warehouses, we offer DDP services (including duties and door-to-door delivery), allowing you to receive goods without the hassle of complex import customs clearance procedures. Please consult your sales manager for specific costs.
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How can I obtain samples? What are the costs?

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If stock is available at an overseas warehouse, we can provide 1–2 kg of samples for free; you only need to cover the local courier fees.
If shipping from China, we can arrange delivery via DHL or FedEx; samples are free, but you bear the international shipping costs. Once a clear intent to cooperate is established, these shipping costs can be deducted from your first order.
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Can the contract price be adjusted if product prices fluctuate?

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We offer a price protection mechanism:
For fixed-price contracts, we do not unilaterally raise prices due to market increases.
If you anticipate a market downturn, we can negotiate floating pricing—settling based on a benchmark price on the date of shipment or arrival—to flexibly manage fluctuations.
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What does your after-sales service include?

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We provide full-lifecycle service:
Usage Guidance: Assistance with adjusting processing parameters (if required).
Complaint Handling: Response within 48 hours and a solution provided within 7 days.
Regular follow-ups: Proactive contact every six months to understand changing needs and optimize supply solutions.
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