Loratadine CAS#79794-75-5

Loratadine CAS#79794-75-5

Fast-acting and Long-lasting Relief:Loratadine provides rapid onset of action with prolonged antihistamine effects, ensuring sustained symptom control.


Non-sedating and Hormone-free:As a second-generation antihistamine, it does not contain hormones and has no significant central nervous system inhibitory effects.


Effective Allergy Symptom Control:It relieves symptoms of allergic rhinitis, such as sneezing, runny nose, and nasal itching, as well as eye irritation and skin allergies like urticaria.


Safe and Well-tolerated:Lacks significant anticholinergic effects, and toxicological studies show no mutagenic or teratogenic risks in animals.


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product description

Product Description of Loratadine CAS#79794-75-5

Loratadine is a second-generation long-acting tricyclic antihistamine for anti-allergy use. It acts fast powerfully without hormones, and is metabolized into more potent desloratadine in vivo.

It competitively blocks histamine H1 receptors to ease allergic symptoms, with few anticholinergic and sedative effects. It relieves allergic rhinitis and chronic urticaria symptoms. Animal tests prove it has no mutagenic or teratogenic risks.


Product Application of Loratadine CAS#79794-75-5

Loratadine is a highly selective antihistamine for peripheral H1 receptors, providing strong and long-lasting effects. It is used in the treatment of allergic conditions such as allergic rhinitis.

As a nationally classified Class II antiallergic drug, it is applied to relieve both nasal and non-nasal symptoms associated with seasonal allergic rhinitis, as well as to alleviate symptoms of chronic urticaria.


Product Information

Parameters


Melting point134-136°C
Boiling point531.3±50.0 °C(Predicted)
density1.261±0.06 g/cm3(Predicted)
RTECSTM6129200
storage temp.2-8°C
solubilityDMSO: 26 mg/mL, soluble
formpowder
pka4.27±0.20(Predicted)
colorwhite
Water SolubilityIt is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck145578
BCS Class2
Stability:Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKeyJCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference79794-75-5(CAS DataBase Reference)
EPA Substance Registry System1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Hazard CodesXi
Risk Statements36/37/38
Safety Statements22-24/25-36-26
RIDADR3077
WGK Germany2
HS Code29333990
Hazardous Substances Data79794-75-5(Hazardous Substances Data)


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We are a supply chain service provider rather than a single manufacturer. Instead of being tied to one specific factory, we have established deep partnerships with numerous high-quality domestic chemical enterprises that hold certifications such as ISO and REACH. This allows us to flexibly match the most suitable supply sources to your needs while independently conducting third-party quality inspections to ensure delivery quality and price competitiveness.
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We maintain transit warehouses with standing inventory in Southeast Asia, the Middle East, and Eastern Europe.
For you: You can pick up goods directly from local warehouses without the need for full-container orders; delivery times are reduced from the standard 30–45 days to just 3–5 days.
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For standard products, the MOQ is typically one 20-foot container (approx. 16–20 tons) for direct shipments from China. However, for stock picked up from overseas warehouses, we support orders starting from 1 ton—ideal for sample testing or small-batch production. Specific MOQs depend on the product category and packaging type; please contact us for details.
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How do you ensure product quality?

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We implement a "three-level quality control" system:
Before leaving the factory: We require the factory to provide a Certificate of Analysis (COA) for the specific batch.
Before shipment: We commission international third-party agencies like SGS or Intertek to conduct random inspections, with costs covered by us (for long-term partners).
After arrival: If quality issues arise, we commit to unconditional negotiation regarding returns, exchanges, or compensation, and we assume full responsibility. All terms are stipulated in the contract.
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FOB (China Port): Goods are prepared and shipped within 7–15 working days after the contract is signed and the prepayment is received.
Overseas Warehouse Stock: Items are dispatched within 1–3 working days of order confirmation and payment; local delivery typically takes 2–5 days (depending on the country).
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Which trade terms do you offer? Do you support DDP (Delivered Duty Paid)?

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We are proficient in handling common terms such as FOB, CIF, CFR, and EXW. Additionally, for regions covered by our overseas warehouses, we offer DDP services (including duties and door-to-door delivery), allowing you to receive goods without the hassle of complex import customs clearance procedures. Please consult your sales manager for specific costs.
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If stock is available at an overseas warehouse, we can provide 1–2 kg of samples for free; you only need to cover the local courier fees.
If shipping from China, we can arrange delivery via DHL or FedEx; samples are free, but you bear the international shipping costs. Once a clear intent to cooperate is established, these shipping costs can be deducted from your first order.
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We offer a price protection mechanism:
For fixed-price contracts, we do not unilaterally raise prices due to market increases.
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We provide full-lifecycle service:
Usage Guidance: Assistance with adjusting processing parameters (if required).
Complaint Handling: Response within 48 hours and a solution provided within 7 days.
Regular follow-ups: Proactive contact every six months to understand changing needs and optimize supply solutions.
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