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Metronidazole CAS#443-48-1

  • Metronidazole CAS#443-48-1
  • Metronidazole CAS#443-48-1
  • Metronidazole CAS#443-48-1
  • Metronidazole CAS#443-48-1
  • Metronidazole CAS#443-48-1

Metronidazole CAS#443-48-1

Effective Anti-anaerobic Activity：Metronidazole has strong bactericidal effects against a wide range of anaerobic microorganisms.


Dual-action Mechanism：Both the drug and its metabolites inhibit bacterial DNA synthesis, effectively stopping bacterial growth and reproduction.


Clinically Proven Efficacy：Recognized by the World Health Organization as a key treatment for anaerobic infections with significant therapeutic results.


Broad Therapeutic Applications：Widely used for the prevention and treatment of various infections, including oral, respiratory, gastrointestinal, abdominal, skin, and systemic infections caused by anaerobic bacteri.

Phone ：+86 18626059817
WhatsApp ：+86 18626059817
Email ：cora@wxqysteel.com
product description

Product Description of Metronidazole CAS#443-48-1

Metronidazole is a nitroimidazole antibiotic active against anaerobic bacteria and Giardia, working by inhibiting bacterial DNA synthesis after metabolic activation. Designated by WHO in 1978 as the drug of choice for anaerobic infections, it was first used for vaginal trichomoniasis and is now widely applied to prevent and treat anaerobic infections throughout the body.


Product Application of Metronidazole CAS#443-48-1

This product has been used since 1959 for the treatment of vaginal trichomoniasis, and since 1970 for intestinal and extraintestinal amoebiasis. It is characterized by high efficacy, low toxicity, and a broad range of applications. However, animal studies have shown potential mutagenic and teratogenic effects.

Metronidazole exhibits strong antibacterial activity against most anaerobic bacteria. It is widely used in the treatment of amoebiasis, trichomoniasis, and various anaerobic infections.


Product Information

Parameters


Melting point159-161 °C (lit.)
Boiling point301.12°C (rough estimate)
density1.3994 (rough estimate)
refractive index1.5800 (estimate)
Fp9℃
storage temp.2-8°C
solubilityacetic acid: 0.1 M, clear, faintly yellow
formcrystalline
pkapKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain)
colorwhite to light yellow
Water Solubility<0.1 g/100 mL at 20 ºC
Merck146157
BRN611683
BCS Class1,3
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyVAOCPAMSLUNLGC-UHFFFAOYSA-N
LogP-0.02
IARC2B (Vol. 13, Sup 7) 1987
NIST Chemistry ReferenceMetronidazole(443-48-1)
EPA Substance Registry SystemMetronidazole (443-48-1)
Hazard CodesXn
Risk Statements40-46-45-39/23/24/25-23/24/25-11
Safety Statements36/37-45-53-16-7
WGK Germany3
RTECSNI5600000
F8
HS Code29332990
Hazardous Substances Data443-48-1(Hazardous Substances Data)


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We are a supply chain service provider rather than a single manufacturer. Instead of being tied to one specific factory, we have established deep partnerships with numerous high-quality domestic chemical enterprises that hold certifications such as ISO and REACH. This allows us to flexibly match the most suitable supply sources to your needs while independently conducting third-party quality inspections to ensure delivery quality and price competitiveness.
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How do your overseas warehouses operate, and what are the practical benefits?

A：
We maintain transit warehouses with standing inventory in Southeast Asia, the Middle East, and Eastern Europe.
For you: You can pick up goods directly from local warehouses without the need for full-container orders; delivery times are reduced from the standard 30–45 days to just 3–5 days.
Reduced inventory pressure: You can purchase small batches for trial and quality verification before scaling up orders, avoiding the need to tie up large amounts of capital upfront.
Emergency restocking: If your production line faces a sudden material shortage, we can urgently dispatch supplies from our regional warehouses to prevent production downtime.
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What is the Minimum Order Quantity (MOQ)?

A：
For standard products, the MOQ is typically one 20-foot container (approx. 16–20 tons) for direct shipments from China. However, for stock picked up from overseas warehouses, we support orders starting from 1 ton—ideal for sample testing or small-batch production. Specific MOQs depend on the product category and packaging type; please contact us for details.
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How do you ensure product quality?

A：
We implement a "three-level quality control" system:
Before leaving the factory: We require the factory to provide a Certificate of Analysis (COA) for the specific batch.
Before shipment: We commission international third-party agencies like SGS or Intertek to conduct random inspections, with costs covered by us (for long-term partners).
After arrival: If quality issues arise, we commit to unconditional negotiation regarding returns, exchanges, or compensation, and we assume full responsibility. All terms are stipulated in the contract.
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What payment methods do you accept? Do you offer credit terms?

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We accept T/T (Telegraphic Transfer), L/C (Letter of Credit at sight or usance), and D/P (Documents against Payment). For clients with a long-standing partnership and good credit standing, we offer partial credit terms (e.g., 30–60 days), subject to negotiation based on transaction history and due diligence results. Cash on Delivery (COD) is available for local customers ordering in-stock items from our overseas warehouses.
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What is the typical delivery lead time?

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FOB (China Port): Goods are prepared and shipped within 7–15 working days after the contract is signed and the prepayment is received.
Overseas Warehouse Stock: Items are dispatched within 1–3 working days of order confirmation and payment; local delivery typically takes 2–5 days (depending on the country).
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Which trade terms do you offer? Do you support DDP (Delivered Duty Paid)?

A：
We are proficient in handling common terms such as FOB, CIF, CFR, and EXW. Additionally, for regions covered by our overseas warehouses, we offer DDP services (including duties and door-to-door delivery), allowing you to receive goods without the hassle of complex import customs clearance procedures. Please consult your sales manager for specific costs.
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How can I obtain samples? What are the costs?

A：
If stock is available at an overseas warehouse, we can provide 1–2 kg of samples for free; you only need to cover the local courier fees.
If shipping from China, we can arrange delivery via DHL or FedEx; samples are free, but you bear the international shipping costs. Once a clear intent to cooperate is established, these shipping costs can be deducted from your first order.
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Can the contract price be adjusted if product prices fluctuate?

A：
We offer a price protection mechanism:
For fixed-price contracts, we do not unilaterally raise prices due to market increases.
If you anticipate a market downturn, we can negotiate floating pricing—settling based on a benchmark price on the date of shipment or arrival—to flexibly manage fluctuations.
Q：

What does your after-sales service include?

A：
We provide full-lifecycle service:
Usage Guidance: Assistance with adjusting processing parameters (if required).
Complaint Handling: Response within 48 hours and a solution provided within 7 days.
Regular follow-ups: Proactive contact every six months to understand changing needs and optimize supply solutions.
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