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Silybin CAS#22888-70-6

  • Silybin CAS#22888-70-6
  • Silybin CAS#22888-70-6
  • Silybin CAS#22888-70-6
  • Silybin CAS#22888-70-6
  • Silybin CAS#22888-70-6

Silybin CAS#22888-70-6

Primary Active Component of Silymarin：Represents 70–80% of the silymarin complex, ensuring high biological potency.


Strong Antioxidant and Anti：Inflammatory Activity – Effectively protects cells against oxidative stress and inflammation.


Broad Pharmacological Benefits：Exhibits anticancer, antidiabetic, antiviral, antimicrobial, and immunomodulatory properties.


Powerful Organ Protection：Provides significant hepatoprotective and neuroprotective effects.


Phone ：+86 18626059817
WhatsApp ：+86 18626059817
Email ：cora@wxqysteel.com
product description

Product Description of Silybin CAS#22888-70-6

Silybin, also referred to as silibinin, is the main biologically active component of the silymarin complex, accounting for approximately 70–80%, and consists of a mixture of silybin A and silybin B. Pharmacological studies have shown that silybin exhibits a wide range of biological activities, including strong antioxidant, anti-inflammatory, anticancer, antidiabetic, hepatoprotective, neuroprotective, antiviral, antimicrobial, and immunosuppressive effects.


Product Application of Silybin CAS#22888-70-6

Silibinin has been applied in various research studies, including:

Investigating its effects on the expression of genes related to chromatin regulation in prostate cancer using real-time polymerase chain reaction (RT-PCR).

Evaluating its influence on cell proliferation in platelet-derived growth factor (PDGF)–treated human Tenon’s fibroblasts (HTFs) by analyzing proliferating cell nuclear antigen (PCNA) expression and conducting water-soluble tetrazolium salt (WST-1) assays.

Examining its impact on the gene expression of stromelysin-1 (STM1), acetyl hexosamines, and collagen synthesis during the process of skin wound healing.

Studying its inhibitory activity against Escherichia coli ATP synthase.


Product Information

Parameters


Melting point164-174°C
alphaD20 +11° (c = 0.25 in acetone + alcohol)
Boiling point793.0±60.0 °C(Predicted)
density1.527±0.06 g/cm3(Predicted)
storage temp.-20°C
solubilityAcetone (Sparingly), DMSO, Methano (Sparingly)
formSolid
pkapKa 6.42±0.04 (Uncertain)
colorPale Yellow
Water Solubility54mg/L(24.99 ºC)
Merck138607
Stability:Stable. Incompatible with strong oxidizing agents, strong bases.
LogP4.232 (est)
CAS DataBase22888-70-6(CAS DataBase Reference)
Reference
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-37/39-24/25-22-36
RIDADR3172
WGK Germany3
RTECSDJ2981770
HS Code29329990
ToxicityLD50 intravenous in mouse: 1056mg/kg


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We are a supply chain service provider rather than a single manufacturer. Instead of being tied to one specific factory, we have established deep partnerships with numerous high-quality domestic chemical enterprises that hold certifications such as ISO and REACH. This allows us to flexibly match the most suitable supply sources to your needs while independently conducting third-party quality inspections to ensure delivery quality and price competitiveness.
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We maintain transit warehouses with standing inventory in Southeast Asia, the Middle East, and Eastern Europe.
For you: You can pick up goods directly from local warehouses without the need for full-container orders; delivery times are reduced from the standard 30–45 days to just 3–5 days.
Reduced inventory pressure: You can purchase small batches for trial and quality verification before scaling up orders, avoiding the need to tie up large amounts of capital upfront.
Emergency restocking: If your production line faces a sudden material shortage, we can urgently dispatch supplies from our regional warehouses to prevent production downtime.
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For standard products, the MOQ is typically one 20-foot container (approx. 16–20 tons) for direct shipments from China. However, for stock picked up from overseas warehouses, we support orders starting from 1 ton—ideal for sample testing or small-batch production. Specific MOQs depend on the product category and packaging type; please contact us for details.
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How do you ensure product quality?

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We implement a "three-level quality control" system:
Before leaving the factory: We require the factory to provide a Certificate of Analysis (COA) for the specific batch.
Before shipment: We commission international third-party agencies like SGS or Intertek to conduct random inspections, with costs covered by us (for long-term partners).
After arrival: If quality issues arise, we commit to unconditional negotiation regarding returns, exchanges, or compensation, and we assume full responsibility. All terms are stipulated in the contract.
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We accept T/T (Telegraphic Transfer), L/C (Letter of Credit at sight or usance), and D/P (Documents against Payment). For clients with a long-standing partnership and good credit standing, we offer partial credit terms (e.g., 30–60 days), subject to negotiation based on transaction history and due diligence results. Cash on Delivery (COD) is available for local customers ordering in-stock items from our overseas warehouses.
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What is the typical delivery lead time?

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FOB (China Port): Goods are prepared and shipped within 7–15 working days after the contract is signed and the prepayment is received.
Overseas Warehouse Stock: Items are dispatched within 1–3 working days of order confirmation and payment; local delivery typically takes 2–5 days (depending on the country).
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Which trade terms do you offer? Do you support DDP (Delivered Duty Paid)?

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We are proficient in handling common terms such as FOB, CIF, CFR, and EXW. Additionally, for regions covered by our overseas warehouses, we offer DDP services (including duties and door-to-door delivery), allowing you to receive goods without the hassle of complex import customs clearance procedures. Please consult your sales manager for specific costs.
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How can I obtain samples? What are the costs?

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If stock is available at an overseas warehouse, we can provide 1–2 kg of samples for free; you only need to cover the local courier fees.
If shipping from China, we can arrange delivery via DHL or FedEx; samples are free, but you bear the international shipping costs. Once a clear intent to cooperate is established, these shipping costs can be deducted from your first order.
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Can the contract price be adjusted if product prices fluctuate?

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We offer a price protection mechanism:
For fixed-price contracts, we do not unilaterally raise prices due to market increases.
If you anticipate a market downturn, we can negotiate floating pricing—settling based on a benchmark price on the date of shipment or arrival—to flexibly manage fluctuations.
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What does your after-sales service include?

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We provide full-lifecycle service:
Usage Guidance: Assistance with adjusting processing parameters (if required).
Complaint Handling: Response within 48 hours and a solution provided within 7 days.
Regular follow-ups: Proactive contact every six months to understand changing needs and optimize supply solutions.
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